Drug "Bonviva": instructions for use

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Drug "Bonviva": instructions for use
Drug "Bonviva": instructions for use
Anonim
bonviva instruction
bonviva instruction

Description of the pharmacological characteristics of the drug

Drug "Bonviva" instruction characterizes as a tool included in the group of highly active bisphosphonates of the nitrogen-containing type. The action of this drug is based on an obstacle to bone destruction provoked by retinoids and blockade of the function of the gonads by tumor extracts and the tumors themselves. It should be especially noted that the "Bonviva" tool, the instructions for which are necessarily included in the kit, does not have any negative effect on the replenishment of the osteoclast pool. In addition, this nitrogen-containing drug does not affect the processes of formation and mineralization of bone tissue and dose-dependently prevents bone resorption. As for the features of the pharmacokinetics of this drug, the time to reach its highest plasma concentration is from thirty to one hundred and twenty minutes, and the half-life varies from ten to seventy-two hours. The latter depends on a particular dosage and individual sensitivity of the body.

Composition and dosage form of release

bonviva medicine
bonviva medicine

The drug "Bonviva" is produced, the instructions for which also indicate this, usually in the form of a colorless, absolutely transparent solution intended for intravenous injection. The medicine is in special syringe tubes with a volume of three milliliters. The composition of this product as the main ingredient includes sodium ibandronate monohydrate. Acetic acid and purified water act as additional substances. In addition, a small amount contains sodium acetate and sodium chloride. It should be especially noted that on sale today you can find this drug in tablets.

Medical indications for use

The instructions recommend using Bonviva to prevent fractures in postmenopausal osteoporosis.

Main contraindications to prescribing the remedy

bonviva instructions
bonviva instructions

It is strictly forbidden to prescribe this nitrogen-containing agent to persons suffering from increased individual sensitivity to ibandronic acid or any of its other components. With hypocalcemia, the drug "Bonviva" should also not be used. Injections with this medicine should not be given to patients with severe renal impairment.

List of possible adverse reactions

Prolonged use of Bonviva may cause abdominal pain, dyspepsia, flatulence, vomiting, dysphagia, nausea, esophagitis or diarrhea. Duodenitis, gastroesophageal reflux, esophageal ulcers, and gastritis may also develop. Myalgia, dizziness, muscle stiffness, arthralgia, headache and muscle spasms can similarly be observed due to the use of the nitrogen-containing preparation Bonviva. This medicine can also provoke the development of a flu-like syndrome, angioedema, urticaria, skin rash, flushing and itching. In addition, in very rare cases, patients complained of osteonecrosis of the jaw as a result of bisphosphonate therapy.

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